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Cannabis, Pregnancy, and Breastfeeding: What the Evidence Actually Shows

A Question With a Clear Answer Some harm reduction questions are genuinely complicated, with evidence that points in ambiguous directions and honest people landing on different sides. This is not one of them. The question of cannabis use during pregnancy and breastfeeding has a scientific consensus that has only strengthened over two decades of accumulating […]

Cannabis Hyperemesis Syndrome: The Vomiting Nobody Expects

The Diagnosis That Surprises Everyone Cannabis has a famous anti-nausea reputation — it's prescribed for chemotherapy patients, it's the go-to for stomach bugs and motion sickness, and for many users a joint reliably settles an uneasy gut. Which is why cannabis hyperemesis syndrome (CHS) is so bewildering, both to patients and to the emergency physicians […]

Synthetic Cannabinoids: Why “Not the Plant” Is Dangerous

A Drug That Isn't What It Claims Synthetic cannabinoids — the compounds sold as "K2," "Spice," "herbal incense," and, increasingly, hidden inside unregulated "mushroom" gummies and vape cartridges — have almost nothing in common with cannabis beyond activating the same receptor. The comparison isn't apples to oranges; it's apples to a class of industrial chemicals […]

Psychedelic Research & Harm Reduction (Series 2)

Educational content series — neutral, no vendor promotion Microdosing: The Evidence Behind the Hype A Phenomenon Out of Nowhere Ten years ago, almost nobody outside Silicon Valley biohacking circles had heard of microdosing — the practice of taking roughly one-tenth to one-twentieth of a recreational dose of a psychedelic, typically psilocybin or LSD, on a […]

How Cannabis Affects the Brain: THC, CBD, and the Endocannabinoid System

Your Brain's Own Cannabis System Here's a fact that surprises most people: your body makes its own cannabinoids. The endocannabinoid system (ECS) — a network of receptors, signaling molecules, and enzymes spread throughout the brain and body — evolved long before humans encountered the cannabis plant. It acts as a kind of master modulator, fine-tuning […]